Author

S. Paramsothy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

J. J. Faith· 3 shared V. Aggarwala· 3 shared A. Grinspan· 2 shared H. Mitchell· 2 shared I. Mogno· 2 shared M. A. Kamm· 2 shared M. C. Dubinsky· 2 shared N. O. Kaakoush· 2 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersMicrobiology

J. J. Faith

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Author profile →

3 papers

Recent·Most cited

Gut microbiota bacterial strain richness is species specific and limits therapeutic engraftment

A. Chen-Liaw, V. Aggarwala, I. Mogno, C. Haifer, J. Eggers, Z. Li, D. Helmus, A. Hart, J. Wehkamp, E. Lamouse-Smith, R. L. Kerby, F. E. Rey, J. F. Colombel, M. Kamm, T. J. Borody, , J. J. Faith

The paper determines strain richness of common gut species and finds it is species-specific and limited in the gut, with temporary increases from therapeutic administration.

bioRxiv · Nov 1, 2022 · PreprintMicrobiology

Strain population structure varies widely across bacterial species and predicts strain colonization in unrelated individuals

J. J. Faith, A. Chen Liaw, V. Aggarwala, N. O. Kaakoush, T. Borody, H. Mitchell, M. A. Kamm, S. Paramsothy, E. S. Snitkin, I. Mogno

The study quantifies strain population sizes across bacterial species and finds prevalent strains in common gut microbiota are more likely to be shared among unrelated individuals.

bioRxiv · Oct 17, 2020 · PreprintMicrobiology

Defined microbiota transplant restores Th17/RORtγ+ regulatory T cell balance in mice colonized with inflammatory bowel disease microbiotas

G. J. Britton, E. J. Contijoch, M. P. Spindler, V. Aggarwala, G. Bongers, L. San Mateo, A. Baltus, A. Das, D. Gevers, T. J. Borody, N. O. Kaakoush, M. A. Kamm, H. Mitchell, S. Paramsothy, J. C. Clemente, , J. J. Faith

The paper shows that transplanting healthy microbiota into mice with IBD microbiotas restores Th17/RORγt+ regulatory T cell balance by reducing pathogenic strains.

bioRxiv · Nov 16, 2019Immunology