Author

S. Raschka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Harris· 2 shared L. Schmitt· 2 shared M. Wagner· 2 shared B. F. Luisi· 1 shared C. Gatsogiannis· 1 shared C. Gertzen· 1 shared D. Blum· 1 shared D. Du· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

A. Harris

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2 papers

Recent·Most cited

A new twist in ABC transporter mediated multidrug resistance - Pdr5 is a drug/proton co-transporter

M. Wagner, D. Blum, S. Raschka, L.-M. Nentwig, C. Gertzen, M. Chen, C. Gatsogiannis, A. Harris, S. Smits, R. Wagner, L. Schmitt

This study shows Pdr5, an ABC transporter, functions as a proton/drug co-transporter, generating a proton motive force during drug efflux, suggesting a more complex mechanism of multidrug resistance.

bioRxiv · May 26, 2021Biochemistry

Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5

A. Harris, M. Wagner, D. Du, S. Raschka, H. Gohlke, S. H. J. Smits, B. F. Luisi, L. Schmitt

This study reveals the structural and functional mechanism of the yeast Pdr5 transporter, showing how it uses ATP to drive drug efflux through a conformational cycle and an amphipathic channel.

bioRxiv · Feb 9, 2021Microbiology