Author

D. Du

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Biochemistry· 1 Biophysics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

B. F. Luisi· 2 shared R. Zhang· 2 shared X. Lu· 2 shared Y. Li· 2 shared Y. Liu· 2 shared Y. Zhang· 2 shared A. Harris· 1 shared A. Neuberger· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

B. F. Luisi

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

How does the ion concentration affect the functions of kinesin BimC

W. Guo, Y. Gao, D. Du, J. Sanchez, A. Visootsat, Y. Li, W. Qiu, L. Li

This study investigates how ion concentration affects BimC's function by analyzing electrostatic interactions between BimC and microtubules using molecular dynamics simulations.

bioRxiv · May 31, 2024Biophysics

Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer

R. Zhang, M. Hu, Y. Liu, W. Li, Z. Xu, S. He, Y. Lu, Y. Gong, X. Wang, S. Hai, S. Li, S. Qi, Y. Li, Y. Shu, D. Du, , L. Dai

This study identifies low tumorous magnesium content as a driver factor of colorectal cancer by showing its impact on gene mutations, EMT activation, and cell migration through DBN1 phosphorylation.

bioRxiv · Jan 22, 2024Cancer Biology

A 4-bp natural deletion of maize Na+/H+ exchanger gene alters maize salt stress tolerance

M. Luo, Y. Zhao, Y. Zhang, R. Zhang, M. Cai, P. Zhang, D. Du, J. Li, J. Xing, X. Sun, M. Duan, X. Lu, Y. Xue, Y. Liu, F. Wang, , J. Zhao

This paper identifies a 4-bp deletion in the maize ZmSOS1 gene that causes salt sensitivity and develops a molecular marker to improve salt tolerance in breeding programs.

bioRxiv · Aug 14, 2022Plant Biology

RBFOX2 deregulation promotes pancreatic cancer metastasis through alternative splicing

M. Maurin, M. Ranjouri, K. Martin, R. Miner, J. Y. Newberg, D. Du, B. Centeno, J. B. Fleming, X. B. Yu, E. Guccione, M. Black, K. M. Mann

This study identifies RBFOX2 deregulation as a driver of pancreatic cancer metastasis through alternative splicing of ABI1, enhancing cancer cell stemness and invasiveness.

bioRxiv · Jun 1, 2022Cancer Biology

Structure and efflux mechanism of the yeast pleiotropic drug resistance transporter Pdr5

A. Harris, M. Wagner, D. Du, S. Raschka, H. Gohlke, S. H. J. Smits, B. F. Luisi, L. Schmitt

This study reveals the structural and functional mechanism of the yeast Pdr5 transporter, showing how it uses ATP to drive drug efflux through a conformational cycle and an amphipathic channel.

bioRxiv · Feb 9, 2021Microbiology

Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins

Y. Zhang, W. Zhao, Y. Mao, Y. Chen, S. Wang, Y. Zhong, T. Su, M. Gong, D. Du, X. Lu, J. Cheng, H. Yang

The paper characterizes site-specific N-glycosylation of SARS-CoV-2 spike proteins expressed in human and insect cells, revealing differences in glycan types and their implications for infection and vaccine development.

bioRxiv · Mar 28, 2020Biochemistry

Interactions of a bacterial RND transporter with a transmembrane small protein in a lipid environment

B. F. Luisi, D. Du, A. Neuberger, M. Orr, C. Newman, P.-C. Hsu, F. Samsudin, A. Szewczak-Harris, L. M. Ramos, M. Debela, S. Khalid, G. Storz

The paper reports cryo-EM structures of AcrB and the AcrBZ complex, showing how AcrZ and lipid interactions modulate AcrB activity.

bioRxiv · Oct 21, 2019Microbiology