An RNA-binding protein secreted by Listeria monocytogenes activates RIG-I signaling
A. Pagliuso, T. N. Tham, E. Allemand, S. Robertin, B. Dupuy, Q. Bertrand, C. Becavin, M. Koutero, V. Najburg, M.-A. Nahori, F. Stavru, A. Dessen, C. Muchard, A. Lebreton, A. V. Komarova, P. Cossart
This study identifies Zea, an RNA-binding protein secreted by L. monocytogenes, which stabilizes bacterial RNAs and activates RIG-I signaling to enhance interferon β production and modulate virulence.
bioRxiv · Mar 17, 2019 · PreprintCell Biology