Immunopeptidomics-based design of highly effective mRNA vaccine formulations against Listeria monocytogenes
R. L. Mayer, R. Verbeke, C. Asselman, I. Aernout, A. Gul, D. Eggermont, K. Boucher, F. Thery, T. M. Maia, H. Demol, R. Gabriels, L. Martens, C. Becavin, S. De Smedt, B. Vandekerckhove, , F. Impens
The paper identifies Listeria monocytogenes epitopes using immunopeptidomics and shows that mRNA vaccines encoding these antigens induce strong immune responses and protection in mice.
bioRxiv · Aug 19, 2022 · PreprintImmunology