Author

S. Saarakkala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Assay:imaging· 5 Approach:experimental assay· 4 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 1 Organism:chicken / avian· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Turkiewicz· 2 shared M. A. J. Finnila· 2 shared M. A. J. Finnilä· 2 shared M. Englund· 2 shared A. Di Giancamillo· 1 shared A. Joukainen· 1 shared A. Kohler· 1 shared A. Mobasheri· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

A. Turkiewicz

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Author profile →

5 papers

Recent·Most cited

Age and anatomical region related differences in vascularization of the porcine meniscus using micro-computed tomography imaging

V.-P. Karjalainen, V. R. Herrera, S. Modina, G. Peretti, M. Pallaoro, K. Elkhouly, S. Saarakkala, A. Mobasheri, A. Di Giancamillo, M. A. J. Finnila

This study uses micro-CT imaging to compare vascularization differences between neonatal and adult porcine menisci across anatomical regions, finding greater vascularity in neonates and thicker vessels in adults.

bioRxiv · Nov 8, 2023Biophysics

Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis

M. Ebrahimi, A. Turkiewicz, M. A. J. Finnila, S. Saarakkala, M. Englund, R. K. Korhonen, P. Tanska

This study examines how structural and compositional changes in human knee cartilage relate to mechanical properties across osteoarthritis stages.

bioRxiv · May 1, 2022Biophysics

Mineral crystal thickness in calcified cartilage and subchondral bone in healthy and osteoarthritic knees

M. A. J. Finnilä, S. Das Gupta, M. J. Turunen, I. Kestilä, A. Turkiewicz, V. Lutz-Bueno, E. Folkesson, M. Holler, N. Ali, V. Hughes, H. Isaksson, J. Tjörnstrand, P. Önnerfjord, M. Guizar-Sicairos, S. Saarakkala, M. Englund

The paper measures mineral crystal thickness in calcified cartilage and subchondral bone of healthy and osteoarthritic knees, finding increased thickness in the unloaded lateral compartment and decreased thickness in subchondral bone with OA severity.

bioRxiv · Jun 15, 2021 · PreprintBiophysics

Infrared fiber optic spectroscopy detects bovine articular cartilage degeneration

V. K. O. Virtanen, E. Nippolainen, R. Shaikh, I. Afara, J. Toyras, J. Solheim, V. Tafintseva, B. Zimmermann, A. Kohler, S. Saarakkala, L. Rieppo

This study uses FTIR-ATR spectroscopy to detect cartilage degeneration in bovine samples, showing high classification accuracy with machine learning models.

bioRxiv · May 18, 2020Biophysics

Automating three-dimensional osteoarthritis histopathological grading of human osteochondral tissue using machine learning on contrast-enhanced micro-computed tomography

S. J. O. Rytky, A. Tiulpin, T. Frondelius, M. A. J. Finnilä, S. S. Karhula, J. Leino, K. P. H. Pritzker, M. Valkealahti, P. Lehenkari, A. Joukainen, H. Kröger, H. J. Nieminen, S. Saarakkala

This paper develops a machine learning method to automatically grade osteoarthritis in 3D CECT images of osteochondral tissue, achieving high accuracy in surface zones.

bioRxiv · Jul 26, 2019Bioengineering