Author

S. Simonsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Organism:yeast· 1

Frequent Co-Authors

A. Prestel· 2 shared B. B. Kragelund· 2 shared A. Carr· 1 shared E. C. Oesterlund· 1 shared G. W. Haxholm· 1 shared H. M. Shamim· 1 shared J. G. Olsen· 1 shared J. Mortensen· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiophysics

A. Prestel

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Author profile →

2 papers

Recent·Most cited

Responses to ligand binding in the bacterial DNA sliding clamp beta-clamp manifest in dynamic allosteric effects

S. Simonsen, A. Prestel, E. C. Oesterlund, M. Otterlei, T. J. D. Jorgensen, B. B. Kragelund

This study investigates how ligand binding affects the dynamics of the bacterial DNA sliding clamp beta-clamp using NMR and hydrogen-deuterium exchange mass spectrometry, revealing dynamic allosteric effects.

bioRxiv · Jun 26, 2024Biophysics

Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs

J. G. Olsen, A. Prestel, N. Kassem, S. S. Broendum, H. M. Shamim, S. Simonsen, M. Grysbaek, J. Mortensen, L. L. Rytkjaer, G. W. Haxholm, R. Marabini, A. Carr, R. Crehuet, O. Nielsen, B. B. Kragelund

The paper identifies a PIP-box motif in Spd1 that competes with another PCNA binding site to regulate checkpoint activation in yeast.

bioRxiv · May 11, 2023Biophysics