Author

S. Spano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 2 Organism:human· 1

Frequent Co-Authors

M. Baldassarre· 3 shared R. A. Colamarino· 2 shared V. Solano-Collado· 2 shared A. Balci· 1 shared D. A. Calderwood· 1 shared D. M. Reid· 1 shared G. D. Brown· 1 shared G. Dougan· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMicrobiology

M. Baldassarre

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Author profile →

3 papers

Recent·Most cited

A small-scale shRNA screen in primary mouse macrophages identifies a role for the Rab GTPase Rab1b in controlling Salmonella Typhi growth

V. Solano-Collado, R. A. Colamarino, D. A. Calderwood, M. Baldassarre, S. Spano

The paper performs a small-scale shRNA screen in mouse macrophages to identify genes controlling Salmonella Typhi growth, finding Rab1b plays a role in restricting the bacterium.

bioRxiv · Dec 1, 2020Microbiology

Lipidation of a bacterial effector is critical for bacterial evasion of host-defense

N. Cattelan, H. Yu, K. Przybyszewska, R. A. Colamarino, M. Baldassarre, S. Spano

This study shows that lipidation of the Salmonella effector GtgE is essential for its membrane targeting and Rab32 inactivation, enabling Salmonella survival in macrophages.

bioRxiv · Nov 5, 2020 · PreprintMicrobiology

The RAB32/BLOC-3 dependent pathway mediates host-defence against different pathogens in human macrophages

M. Baldassarre, V. Solano-Collado, A. Balci, R. Colamarino, I. M. Dambuza, D. M. Reid, H. M. Wilson, G. D. Brown, S. Mukhopadhyay, G. Dougan, S. Spano

This study identifies the Rab32/BLOC-3 pathway as a novel host-defense mechanism in macrophages that protects against bacterial and fungal pathogens.

bioRxiv · Jan 15, 2020 · PreprintMicrobiology