RGG motif-containing Scd6/LSM14A proteins regulate the translation of specific mRNAs in response to hydroxyurea-induced genotoxic stress
G. Mohanan, R. Roy, H. Malka-Mahieu, S. Lamba, L. Fabbri, A. Biswas, S. Martineau, C. Labbe, S. Vagner, P. I. Rajyaguru
This study identifies Scd6/LSM14A proteins as regulators of mRNA translation during hydroxyurea-induced genotoxic stress, showing their role in modulating SRS2 and NHEJ factor mRNAs through arginine methylation.
bioRxiv · Jul 12, 2022 · PreprintCell Biology