Cancer BiologybioRxiv
Pre-existing Subclones Determine Radioresistance in Rectal Cancer Organoids
D. Andel, B. Viergever, N. Peters…·O. Kranenburg
This study shows that pre-existing subclones in rectal cancer organoids determine radioresistance, with resistance linked to reduced chromosomal instability.
DOI 10.1016/j.celrep.2024.113735