Identification of a primitive intestinal transcription factor network shared between oesophageal adenocarcinoma and its pre-cancerous precursor state
C. Rogerson, E. Britton, S. Withey, N. Hanley, Y. Ang, A. D. Sharrocks
This study identifies a primitive intestinal transcription factor network, centered on HNF4A and GATA6, that is active in oesophageal adenocarcinoma and its precursor state, Barretts oesophagus.
bioRxiv · Jul 30, 2018Cancer Biology