E. Britton

Identification of leptospiral protein antigens recognized by WC1+ γδ T cell subsets as target for development of recombinant vaccines

The paper identifies two leptospiral outer membrane proteins that activate WC1+ γδ T cells, providing targets for recombinant vaccine development.

Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to Oesophageal Adenocarcinoma

The paper identifies a cell cycle gene expression signature in Oesophageal Adenocarcinoma (OAC) and shows KLF5's repurposing to regulate cell cycle genes during progression from Barrett's oesophagus to OAC.

Identification of a primitive intestinal transcription factor network shared between oesophageal adenocarcinoma and its pre-cancerous precursor state

This study identifies a primitive intestinal transcription factor network, centered on HNF4A and GATA6, that is active in oesophageal adenocarcinoma and its precursor state, Barretts oesophagus.

Metagenomic next-generation sequencing reveals Miamiensis avidus (Ciliophora: Scuticociliatida) in the 2017 epizootic of leopard sharks (Triakis semifasciata) in San Francisco Bay, California

The paper uses metagenomic sequencing to identify Miamiensis avidus in leopard sharks during a 2017 epizootic, linking it to meningoencephalitis and highlighting its presence in wild elasmobranchs for the first time.