SMAD6 Integrates Endothelial Cell Homeostatic Flow Responses Downstream of Notch
D. L. Ruter, Z. Liu, K. M. Ngo, S. X, A. Marvin, D. B. Buglak, E. J. Kidder, V. L. Bautch
This study shows SMAD6 is essential for endothelial cell alignment under laminar shear flow, downstream of Notch1, and its loss disrupts barrier function and gene expression.
bioRxiv · Jul 2, 2020Cell Biology