Plant BiologybioRxiv
Endoplasmic Reticulum Retention Motif Fused to Recombinant Anti-cancer Monoclonal Antibody (mAb) CO17-1A Affects mAb Expression and Plant Stress Response
I. Song, Y. J. Kang, Y. K. Lee…·K. Ko
This paper shows that adding the KDEL motif to an anti-cancer mAb increases its expression in transgenic Arabidopsis but also causes ER stress and slightly reduces plant biomass.
DOI 10.1371/journal.pone.0198978