Sabine Hamm

The adhesion molecules β7 integrin and L-selectin contribute to cholestatic liver disease in male mice

This study shows that β7 integrin and L-selectin contribute to DDC-induced cholangiopathy in male mice by promoting immune cell infiltration, gut barrier dysfunction, and microbiota shifts.

Intercellular adhesion molecule-1 protects against adipose tissue inflammation and insulin resistance but promotes liver inflammation and hepatic fibrosis in mice

This study shows ICAM-1 protects against adipose tissue inflammation and insulin resistance but worsens liver inflammation and fibrosis in mice with diet-induced obesity.