Solid immersion microscopy readily and inexpensively enables 12 nm resolution on plunge-frozen cells
Lin Wang, Benji Bateman, Laura C. Zanetti-Domingues, Amy N. Moores, Sam Astbury, Christopher Spindloe, Michele C. Darrow, Maria Romano, Sarah R. Needham, Konstantinos Beis, Daniel J. Rolfe, David T. Clarke, Marisa L. Martin-Fernandez
This paper introduces a low-cost solid immersion lens technique that achieves 12 nm resolution in cryogenic fluorescence microscopy, outperforming more expensive systems.
bioRxiv · Jul 20, 2018 · PreprintBiophysics