Author

Sam Pledger

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Mark Christopher ColesiD· 3 shared Christopher Dominic BuckleyiD· 2 shared Dylan WindelliD· 2 shared Aime PalomerasiD· 1 shared Amy WardiD· 1 shared Ananya BhallaiD· 1 shared Andrew D. DickiD· 1 shared Andrew D. FoersiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

Mark Christopher ColesORCID

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3 papers

Recent·Most cited

Tissue resident memory T cells populate the human uveal tract

Andrew D. Foers, Ian R. Reekie, Lakshanie C. Wickramasinghe, Amy Ward, Thomas M. W. Buckley, Moustafa Attar, Soledad Aguilar-Munoa, Queen Pilapil, Maram E. A. Abdalla Elsayed, Sam Pledger, Ananya Bhalla, Robert Hedley, Sarah Hill, Dylan Windell, Keith Barton, , Colin J. Chu

The paper identifies resident memory T cells in the human uveal tract, showing their presence in both healthy and inflamed states and their potential role in uveitis.

Scientific Reports · Apr 3, 2026Peer-reviewedImmunology

Early regional lymph node activation drives influenza vaccine responses in an ancestrally diverse cohort

Jacqueline H. Y. Siu, Sofia Coelho, Aime Palomeras, Sandra Belij‐Rammerstorfer, Ninisha Barman, Chloe Hyun-Jung Lee, Tamara Ströbel, Christopher J. Thorpe, Charandeep Kaur, Tom Cole, Nico Remmert, Jamie Fowler, Sam Pledger, Kyla Dooley, Terrence Chan, , Katrina M. Pollock

This study examines immune responses in ancestrally diverse individuals after influenza vaccination, finding that draining lymph nodes show rapid activation and specific cellular changes.

EBioMedicine · Nov 29, 2025Peer-reviewedImmunology

The ontogeny of myeloid-stromal synovial tissue niches in rheumatoid arthritis.

Aziza Elmesmari, Domenico Somma, Lucy MacDonald, Jack Frew, Zuzanna Kuczynska, Clara Di Mario, Lavinia Agra Coletto, Shravani Baruah, Denise Campobasso, Theodoros Simakou, Eva M.L. Philippon, Sander W. Tas, Marcus Doohan, Roberta Benvenuto, Dario Bruno, , Mariola Kurowska‐Stolarska

This study shows human synovial tissue-resident macrophages develop from monocytes guided by fibroblast-derived cues in specific spatial niches, using a novel organoid system.

bioRxiv · Oct 29, 2025 · PreprintImmunology