Holding glycolysis in check though Alox15 activity is required for macrophage M2 commitment and function in tissue repair and anti-helminth immunity.
Dovran Ovezgeldiyev, Vanessa Trefzer, Rory Doolan…·Tiffany Bouchery
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University of OxfordORCID 0000-0001-8733-2945Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Dovran Ovezgeldiyev, Vanessa Trefzer, Rory Doolan…·Tiffany Bouchery
Andrew D. Foers, Ian R. Reekie, Lakshanie C. Wickramasinghe…·Colin J. Chu
The paper identifies resident memory T cells in the human uveal tract, showing their presence in both healthy and inflamed states and their potential role in uveitis.
Célia Sourd, Joel Quinn, Molly C. John…·Kanmin Xue
This study uses single-cell and spatial transcriptomics to analyze immune responses in non-human primates after retinal gene therapy, identifying persistent immune infiltration and cytokine-driven inflammation.
Haozhe Wang, Kristian T. Barry, Aidil Zaini…·Nicola Laraine Harris
This study shows that helminth-induced intestinal hypermotility in mice is driven by smooth muscle changes, not eosinophils or the enteric nervous system.