Cancer BiologybioRxivPreprint
Human iPSC-derived prostate organoids with germline BRCA2 mutation undergo tumorigenic transformations
Bipul R. Acharya, George M. Lawless, Pablo Avalos…·Clive N. Svendsen
This study develops iPSC-derived prostate organoids with and without BRCA2 mutations, showing tumorigenic changes and cancer markers in mutated organoids.
DOI 10.1101/2025.08.26.672478