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Sara Yanke

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Pharmacology & Toxicology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

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David PekkeriD· 1 shared Monica McArthuriD· 1 shared Steven KuntziD· 1 shared Swagatam MukhopadhyayiD· 1 shared T. Nicholson-ShawiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperPharmacology & Toxicology

David PekkerORCID

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Pharmacology & ToxicologybioRxivPreprintMay 28, 2024

A Dose-Response Model for Accurate Detection and Quantification of Transcriptome-Wide Gene Knockdown for Oligonucleotide-Based Medicines

David Pekker, Steven Kuntz, Monica McArthur…·Swagatam Mukhopadhyay

The paper develops a dose-response model and analysis tool to accurately quantify gene knockdown effects of oligonucleotide-based medicines using next-generation sequencing data.

DOI 10.1101/2024.05.28.596270

bulk RNA-seqstatistical model

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