Molecular BiologyMolecular CellPeer-reviewed
Nascent transcript folding plays a major role in determining RNA polymerase elongation rates
Tomasz W. Turowski, Elisabeth Petfalski, Benjamin D. Goddard…·David W. Tollervey
The paper investigates how nascent transcript folding and G+C-content influence RNA polymerase elongation rates in vivo and confirms these effects through in vitro experiments and a mathematical model.