Author

Sasha Pantel

Broad Institute

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Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Amy B. GoodaleiD· 1 shared Ann E. SizemoreiD· 1 shared Aviad TsherniakiD· 1 shared Barbara A. Weir· 1 shared David E. RootiD· 1 shared Derek Hawes· 1 shared Francisca VázqueziD· 1 shared Glenn S. CowleyiD· 1 shared

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2017-2017 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Amy B. GoodaleORCID

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1 paper

Recent·Most cited

GenomicsNature GeneticsPeer-reviewedOct 30, 2017

Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

Robin M. Meyers, Jordan Bryan, James M. McFarland…·Aviad Tsherniak

The paper develops CERES, a computational method to correct copy-number effects in CRISPR-Cas9 essentiality screens, improving specificity in cancer cell line studies.

1,951 citationstop 1%

humanCRISPR screen

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