Author

Seth McGonigle

University of Minnesota

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Alessandro BartolomucciiD· 1 shared Alfonso AraqueiD· 1 shared Audrey L. DaughertyiD· 1 shared Bianca VezzaniiD· 1 shared Carmen NanclaresiD· 1 shared Colleen L. ForsteriD· 1 shared Daniele Lettieri‐BarbatoiD· 1 shared Gianluigi VegliaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alessandro BartolomucciORCID

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1 paper

Recent·Most cited

Complement 3a Receptor mediates high fat diet induced hypothalamic accumulation of lipid associated microglia to regulate neuroinflammation and obesity

Jean Pierre Pallais, Maria Razzoli, Pedro Rodriguez, Audrey L. Daugherty, Seth McGonigle, Bianca Vezzani, Hannah Hillman, Luca Verteramo, Patricia R. Schrank, Preethy Parthiban, Xuechun Chang, Haiguang Wang, Colleen L. Forster, Carmen Nanclares, Gianluigi Veglia, , Alessandro Bartolomucci

This study identifies C3aR as a mediator of HFD-induced hypothalamic microgliosis and obesity, showing its role in lipid droplet formation and neuroinflammation.

Journal of Neuroinflammation · Oct 1, 2026Peer-reviewedImmunology