Author

Patricia R. Schrank

University of MinnesotaORCID 0000-0001-5095-7896Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hannah HillmaniD· 3 shared Jesse W. WilliamsiD· 3 shared Bryce Anthony BinstadtiD· 2 shared Michael T. PattersoniD· 2 shared Xavier S. ReveloiD· 2 shared Yingzheng XuiD· 2 shared Ainsley E. Kennedy· 1 shared Ainsley Kennedy· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Hannah HillmanORCID

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3 papers

Recent·Most cited

ImmunologyJournal of NeuroinflammationPeer-reviewedOct 1, 2026

Complement 3a Receptor mediates high fat diet induced hypothalamic accumulation of lipid associated microglia to regulate neuroinflammation and obesity

Jean Pierre Pallais, Maria Razzoli, Pedro Rodriguez…·Alessandro Bartolomucci

This study identifies C3aR as a mediator of HFD-induced hypothalamic microgliosis and obesity, showing its role in lipid droplet formation and neuroinflammation.

DOI 10.1186/s12974-026-04063-z

mousebulk RNA-seq

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ImmunologybioRxivPreprintMay 21, 2026

Adrenal Gland Macrophage-derived TGF-β Governs Vascular Permeability to Drive Monocyte Recruitment during Stress

Yingzheng Xu, Michael T. Patterson, Michael D. Chang…·Jesse W. Williams

DOI 10.64898/2026.05.18.726080

mousescRNA-seq

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ImmunologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewedMay 2, 2024

Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability

Michael T. Patterson, Yingzheng Xu, Hannah Hillman…·Jesse W. Williams

This study shows that a Trem2 agonist increases plaque macrophage survival and proliferation while improving plaque stability by enhancing collagen deposition and reducing necrotic core size.

83 citationstop 1%

mousebulk RNA-seq

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