Author

Sharon Leonard

West Virginia University

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Biophysics· 1

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Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

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Adam Skeens· 1 shared Adewale AdegbuyiroiD· 1 shared Alyssa R. StonebrakeriD· 1 shared Blake MertziD· 1 shared Chathuranga Siriwardhana· 1 shared Faezeh Sedighi· 1 shared Justin A. LegleiteriD· 1 shared Maryssa A. BeasleyiD· 1 shared

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Adam Skeens

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Recent·Most cited

BiophysicsbioRxivPreprintJul 17, 2024

Blocking the ability of huntingtin to bind membranes: a therapeutic strategy for Huntingtons disease

Chathuranga Siriwardhana, Adewale Adegbuyiro, Faezeh Sedighi…·Justin A. Legleiter

This study evaluates blocking huntingtin membrane binding as a therapeutic strategy for HD, identifying two compounds that alleviate HD phenotypes in C. elegans.

1 citation

C. elegansmechanistic / dynamical model

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