Author

Shiyu Chen

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Developmental Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Changpeng Li· 1 shared Dajiang QiniD· 1 shared Fei MengiD· 1 shared Haitao ZhangiD· 1 shared Han SuniD· 1 shared Haokun Guo· 1 shared Hui ZhengiD· 1 shared Jing LuoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Changpeng Li

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2 papers

Recent·Most cited

The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis

Meiai He, Lining Liang, Yulu Wang, Yongyu Chen, Han Sun, Lin Guo, Changpeng Li, Jingcai He, Yanhua Wu, Shiyu Chen, Tingting Yang, Fei Meng, Qiwen Ren, Linna Dong, Lin Liu, , Hui Zheng

This study shows that the Par complex regulates cell polarity and differentiation by modulating FAK signaling through the AKT-FURIN-LEFTY pathway in mouse embryonic stem cells.

bioRxiv · Oct 2, 2026 · PreprintDevelopmental Biology

Inhibition of CKAMP44 attenuated seizure activity via protein phosphatase 3 regulatory subunit B-mediated GluA1 phosphorylation and synaptic transmission

Lihong Huang, Shiyu Chen, Haokun Guo, Haitao Zhang, L Wang, Xiaoqin Wang, Yiming Guo, Shiyun Yuan, Jing Luo, Long Yang, Weihua Yu

This study shows that inhibiting CKAMP44 reduces seizure activity in TLE by increasing GluA1 phosphorylation and synaptic transmission through PPP3r2 regulation.

bioRxiv · Apr 23, 2026 · PreprintPathology