Chromatin context-dependent deacetylation by the asymmetric Rpd3L
Hongyun Zhao, Huadong Li, Chi Wang…·Jun He
This study reveals how the Rpd3L complex uses an asymmetric architecture to activate deacetylation in response to chromatin context.
Author
Chinese Academy of Sciences
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Hongyun Zhao, Huadong Li, Chi Wang…·Jun He
This study reveals how the Rpd3L complex uses an asymmetric architecture to activate deacetylation in response to chromatin context.
Dan Xiang, Xiaoxiao Tang, Ruona Shi…·Xiaofei Zhang
This study elucidates the catalytic and regulatory mechanisms of hUBE2O, revealing its unique architecture for mono- and polyubiquitination and identifying key residues and zinc ions as regulators.
Silin Li, Zengxuan Zhou, Wan Ching Yu…·Jinhu Guo
The paper reconstructs an ancient cyanobacterial circadian clock from ~0.95 billion years ago and shows it adapts to 18-h day-night cycles but lacks endogenous oscillation.