Author

Sigrid C. Schwarz

German Center for Neurodegenerative Diseases

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alpha Tom KodamulliliD· 1 shared Anastasia IllarionovaiD· 1 shared Ashutosh DhingraiD· 1 shared Daniel Domingo‐FernándéziD· 1 shared Eldem SadikoglouiD· 1 shared Günter U. HöglingeriD· 1 shared Natalia SavytskaiD· 1 shared Noémia FernandesiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperNeuroscience

Alpha Tom KodamullilORCID

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1 paper

Recent·Most cited

NeuroscienceCell Death and DiseasePeer-reviewedNov 13, 2025

Rescue of the increased susceptibility to Mild Chronic Oxidative Stress of iNeurons carrying the MAPT Chromosome 17q21.3 H1/H1 risk allele by FDA-approved compounds

Eldem Sadikoglou, Daniel Domingo‐Fernándéz, Natalia Savytska…·Peter Heutink

The paper investigates how the H1/H1 risk allele at the MAPT locus increases susceptibility to mild chronic oxidative stress in iNeurons and identifies FDA-approved compounds that rescue this vulnerability.

DOI 10.1038/s41419-025-08147-1

humanexperimental assay

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