NeurosciencebioRxivPreprint
ATP13A2 Loss of Function-Driven Polyamine Dysregulation Induces SAM Depletion and Epigenetic Astrocyte Toxicity
Elena Coccia, Gustavo Morrone Parfitt, Sundas Ijaz…·Joel Blanchard
The paper shows ATP13A2 loss of function disrupts polyamine metabolism, leading to SAM depletion and epigenetic astrocyte toxicity, which contributes to Parkinson's disease.