Author
Wellcome Sanger Institute
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Emanuel Gonçalves, Mark Thomas, Fiona M. Behan…·Mathew J. Garnett
The paper designs a smaller genome-wide CRISPR-Cas9 library with reduced size while maintaining sensitivity and specificity, enhancing its applicability in complex models.
Theodoros I. Roumeliotis, Steven P. Williams, Emanuel Gonçalves…·Jyoti Sharma Choudhary
The paper quantifies proteomic and genomic variation in colorectal cancer cell lines to understand how mutations affect protein levels and drug responses.
Jonathan S. Brammeld, Mia Petljak, Iñigo Martincorena…·Ultan McDermott
This paper describes a method to identify drug resistance mutations in cancer using genome-wide chemical mutagenesis and next-generation sequencing, enabling the discovery of both known and novel resistance mechanisms.