Author

Stephanie Higgins

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:metagenomics· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron T. TimpermaniD· 1 shared Abdurrahman ElbasiriD· 1 shared Ahmed M Moustafa· 1 shared Ahmed M. MoustafaiD· 1 shared Alexander Chan Chi HuangiD· 1 shared Anastasia Lucas· 1 shared Andrew D. MarquesiD· 1 shared Bryant Duong· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

Aaron T. TimpermanORCID

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2 papers

Recent·Most cited

Optimizing methods for virome analysis based on studies of a synthetic viral community

Jiayi Duan, Andrew D. Marques, Matthew Hogenauer, Young Hwang, Yanjia Zhang, Aaron T. Timperman, Stephanie Higgins, Naomi G. Wilson, Elizabeth Aine Fitts, Haeun Karissa Lim, Kyle L. Bittinger, Ahmed M Moustafa, Ronald G. Collman, Frederic D. Bushman

This paper evaluates virome analysis methods using a synthetic viral community, finding that VLP enrichment improves read yields and longer sequencing cycles enhance genome assembly.

mSystems · Jun 2, 2026Peer-reviewedMicrobiology

Taxonomy-free fecal microbiome profiles enable robust prediction of immunotherapy response and toxicity in melanoma

Anastasia Lucas, McKenna Reale, Yuri I. Wolf, Bryant Duong, Yichi Zhang, Jayamanna M. Wickramasinghe, Lindsey Behlman, Steven M. Jones, Stephanie Higgins, Ahmed M. Moustafa, Abdurrahman Elbasir, Ravi K. Amaravadi, Tara C. Mitchell, Alexander Chan Chi Huang, Noam Auslander

This study identifies microbiome-derived protein biomarkers for predicting immunotherapy response and toxicity in melanoma without relying on taxonomic classification.

bioRxiv · Nov 6, 2025 · PreprintCancer Biology