T. Bjarnsholt

A method for separating bacterial cultures into single cells and defined size fractions of biofilm aggregates

The paper describes a method to separate bacterial cultures into single cells and biofilm aggregates using mesh filters, validated by microscopy and DNA quantification.

What is Slough?A pilot study to define the proteomic and microbial composition of wound slough and its implications for wound healing.

This study characterizes the proteomic and microbial composition of wound slough and integrates these with clinical data to predict wound healing outcomes.

Inhibition of Pseudomonas aeruginosa quorum sensing by chemical induction of the MexEF-oprN efflux pump

The paper identifies two compounds that inhibit quorum sensing in Pseudomonas aeruginosa by inducing the MexEF-oprN efflux pump, reducing QS-regulated virulence factors.

Biofilms and core pathogens shape the tumour microenvironment and immune phenotype in colorectal cancer

The paper investigates how biofilms and core pathogens like Bacteroides fragilis and Fusobacterium nucleatum influence the tumor microenvironment and immune phenotype in colorectal cancer.

Metabolic flux fingerprinting differentiates planktonic and biofilm states of Pseudomonas aeruginosa and Staphylococcus aureus

This study uses microcalorimetry and machine learning to classify planktonic and biofilm states of Pseudomonas aeruginosa and Staphylococcus aureus with high accuracy.

The origin of extracellular DNA in bacterial biofilm infections in vivo

The paper investigates the origin of extracellular DNA in Pseudomonas aeruginosa biofilm infections in vivo, finding that most eDNA is external to biofilms and derived from the host.

Oxygen Restriction Generates Difficult-To-Culture Pathogens

This study shows that oxygen restriction induces a difficult-to-culture state in bacteria, complicating diagnostic culturing, especially in chronic infections.

Light assisted antibiotics

This study shows that specific ultraviolet wavelengths can effectively kill bacterial biofilms, reducing the need for antibiotics and improving treatment efficacy when combined with them.