M. Andersson

The role of endospore appendages in spore-spore contacts in pathogenic bacilli

This study investigates the role of S-ENAs and L-ENAs in spore-spore contacts and their interaction with vegetative cells, revealing their importance in self-aggregation and environmental factors' impact.

A community-curated, global atlas of Bacillus cereus sensu lato genomes for epidemiological surveillance

The paper develops BTyperDB, a global atlas of Bacillus cereus sensu lato genomes, to improve pathogen surveillance and identify emerging lineages.

A hybrid CNN-Random Forest algorithm for bacterial spore segmentation and classification in TEM images

The paper introduces a hybrid CNN-Random Forest algorithm for segmenting and classifying bacterial spore layers in TEM images, achieving better robustness and generalization than other classifiers.

Physico-chemical characterization of single bacteria and spores using optical tweezers

This paper uses optical tweezers to characterize single bacteria and spores, assessing physico-chemical properties related to adhesion, fluid dynamics, biochemistry, and metabolic activity.

Copper binding leads to increased dynamics in the regulatory N-terminal domain of full-length human copper transporter ATP7B

This study uses molecular dynamics simulations to show that copper binding increases dynamics in the N-terminal regulatory domain of ATP7B by altering interactions between metal-binding domains and the core protein.

Reactive oxygen species generated by infrared laser light in optical tweezers inhibits the germination of bacterial spores

This study shows that infrared laser light inhibits Bacillus thuringiensis spore germination, with oxygen playing a key role in this effect.

Unveiling molecular interactions that stabilize bacterial adhesion pili

This study investigates the biophysical function and structural interactions of P pili from uropathogenic bacteria, revealing how subunit interactions and the N-terminal staple region stabilize the helical filament structure.

PcoB is a defense outer membrane protein that facilitates cellular uptake of copper

This study characterizes PcoB, an outer membrane protein that facilitates copper import, revealing its structure and function in Cu homeostasis and defense against metal stress.

Structure and ion-release mechanism of PIB-4-type ATPases

The paper presents structures and functional analyses of a PIB-4-type ATPase, revealing novel mechanisms of heavy-metal transport and potential drug targets.

Axonal T2 estimation using the spherical variance of the strongly diffusion-weighted MRI signal

This paper introduces a method to estimate axonal T2 using spherical variance of strongly diffusion-weighted MRI signals, showing it is less affected by isotropic contributions compared to spherical mean.

Impact of an alpha helix and a cysteine-cysteine disulfide bond on the resistance of bacterial adhesion pili to stress

This study investigates structural and biophysical differences in bacterial adhesion pili from urinary and intestinal pathogens, finding that disulfide bonds and alpha helices enhance resistance to stress in urinary tract bacteria.

Disinfection chemicals mode of action on the bacterial spore structure and their Raman spectra

This study uses Raman spectroscopy to analyze changes in Bacillus thuringiensis spores after treatment with disinfectants, finding structural and spectral differences that correlate with spore viability.

Multi-omic surveillance of Escherichia coli and Klebsiella spp. in hospital sink drains and patients

The paper shows hospital sink drains are colonized by diverse E. coli and Klebsiella strains, including resistant ones, and may contribute to patient infections.

Evaluation of Different PCR Assay Formats for Sensitive and Specific Detection of SARS-CoV-2 RNA

The paper evaluates different PCR formats for SARS-CoV-2 RNA detection, finding that nested PCR with agarose gel electrophoresis is sensitive and specific but has variable sensitivity depending on transcript length.

Correlating single-molecule characteristics of the yeast aquaglyceroporin Fps1 with environmental perturbations directly in living cells

The paper tracks single-molecule characteristics of the yeast aquaglyceroporin Fps1 in real time under varying environmental conditions using super-resolved fluorescence microscopy.

Optimizing DNA extraction methods for Nanopore sequencing of Neisseria gonorrhoeae direct from urine samples

This study optimizes DNA extraction methods for Nanopore sequencing of Neisseria gonorrhoeae directly from urine samples to enable culture-free whole-genome reconstruction.

Reconciling the potentially irreconcilable? Genotypic and phenotypic amoxicillin-clavulanate resistance in Escherichia coli

This study shows that amoxicillin-clavulanate resistance in E. coli is quantitative, not binary, and that WGS-based predictions outperform traditional phenotyping methods.

Metagenomic Nanopore sequencing of influenza virus direct from clinical respiratory samples

This study uses metagenomic Nanopore sequencing to detect influenza virus in clinical respiratory samples, achieving high sensitivity and complete genome sequencing.

Oxygen Restriction Generates Difficult-To-Culture Pathogens

This study shows that oxygen restriction induces a difficult-to-culture state in bacteria, complicating diagnostic culturing, especially in chronic infections.

Whole genome sequencing for predicting clarithromycin resistance in Mycobacterium abscessus

This study uses whole genome sequencing to predict clarithromycin resistance in Mycobacterium abscessus by identifying known and novel resistance-determining mutations.

Human Herpes Virus 6 (HHV-6) - Pathogen or Passenger? A pilot study of clinical laboratory data and next generation sequencing

This study examines HHV-6 prevalence in clinical samples using PCR and NGS, finding 33% positivity in hematology patients and 20% detection via NGS in CSF and respiratory samples.

Hepatitis B Virus Infection as a Neglected Tropical Disease

The paper examines HBV infection through the lens of neglected tropical diseases and highlights challenges in elimination efforts.