ImmunologybioRxiv
A TIR-1/SARM1 phase transition underlies p38 immune pathway activation in the C. elegans intestine
N. D. Peterson, J. D. Icso, J. E. Salisbury…·R. Pukkila-Worley
This paper shows that a phase transition of TIR-1/SARM1 in C. elegans activates the p38 immune pathway, linking protein oligomerization to immune response and pathogen defense.
DOI 10.7554/elife.74206