Author

T. Caval

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Cevirgel· 1 shared A. E. H. Bentlage· 1 shared A. J. R. Heck· 1 shared A. M. D. Becker· 1 shared A. Tankasala· 1 shared C. G. Figdor· 1 shared C. Guerrier· 1 shared C. M. Le Gall· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

A. Cevirgel

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Variable PD-1 glycosylation modulates the activity of immune checkpoint inhibitors

C.-W. Chu, T. Caval, F. Alisson-Silva, A. Tankasala, C. Guerrier, G. Czerwieniec, H. Laeubli, F. Schwarz

This study shows that PD-1 glycosylation variants affect the efficacy of immune checkpoint inhibitors and suggests personalized therapeutic approaches.

bioRxiv · Aug 25, 2023Immunology

Functional diversification of hybridoma produced antibodies by CRISPR/HDR genomic engineering

J. M. S. van der Schoot, F. L. Fennemann, M. Valente, Y. Dolen, I. M. Hagemans, A. M. D. Becker, C. M. Le Gall, D. van Dalen, A. Cevirgel, J. A. C. van Bruggen, M. Engelfriet, M. F. Fransen, T. Caval, A. E. H. Bentlage, M. Nederend, , F. A. Scheeren

This study presents a CRISPR/HDR platform to engineer hybridoma antibodies for diverse isotypes, formats, and species, enabling functional antibody diversification.

bioRxiv · Feb 15, 2019Bioengineering