3D modeling of CpG DNA binding with matrix lumican shows leucine-rich repeat motif involvement as in TLR9- CpG DNA interactions
T. Choi, G. Maiti, S. Chakravarti
This study models the 3D structure of lumican-CpG DNA interactions, identifying key amino acids and suggesting lower binding strength compared to TLR9-CpG DNA.
bioRxiv · Aug 21, 2023Immunology