Three-dimensional assessments are necessary to determine the true, spatially-resolved composition of tissues
A. Forjaz, E. Vaz, V. M. Romero, S. Joshi, A. M. Braxton, A. C. Jiang, K. Fujikura, T. Cornish, S.-M. Hong, R. H. Hruban, P.-H. Wu, L. D. Wood, A. L. Kiemen, D. Wirtz
This study shows that 3D assessments are necessary to accurately determine tissue composition and neoplastic content, as 2D methods under-sample spatial heterogeneity.
bioRxiv · Dec 4, 2023Cancer Biology