Author

T. Dixon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

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Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Dickson· 2 shared A. Evdokimov· 1 shared A. M. Razavi· 1 shared A. Uyar· 1 shared A. Vinitsky· 1 shared B. Mostofian· 1 shared B. Ruprecht· 1 shared D. MacPherson· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

A. Dickson

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Author profile →

2 papers

Recent·Most cited

Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange

T. Dixon, D. MacPherson, B. Mostofian, T. Dauzhenka, S. Lotz, D. McGee, S. Shechter, U. Shrestha, R. Wiewiora, Z. A. McDargh, F. Pei, R. Pal, J. V. Ribeiro, T. Wilkerson, V. Sachdeva, , J. A. Izaguirre

This paper predicts atomic-resolution structures of degrader-mediated ternary complexes using combined HDX-MS and molecular dynamics simulations, validated by experimental data.

bioRxiv · Sep 26, 2021 · PreprintBiophysics

Membrane-mediated ligand unbinding of the PK-11195 ligand from the translocator protein (TSPO)

T. Dixon, A. Uyar, S. Ferguson-Miller, A. Dickson

This study uses molecular dynamics simulations to show PK-11195 dissociates from TSPO via the lipid membrane, not directly into solvent, with implications for designing long-residence-time ligands.

Biophysical Journal · Jan 1, 2021Peer-reviewedBiophysics