Author

F. Pei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Y. Li· 2 shared A. Dickson· 1 shared A. Evdokimov· 1 shared A. M. Razavi· 1 shared A. Vinitsky· 1 shared B. Mostofian· 1 shared B. Ruprecht· 1 shared C. Zhong· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Y. Li

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Author profile →

2 papers

Recent·Most cited

CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer

C. Zhong, W.-J. Jiang, Y. Yao, Z. Li, Y. Li, S. Wang, X. Wang, W. Zhu, S. Wu, J. Wang, S. Fan, S. Ma, Y. Liu, H. Zhang, W. Zhao, , T. Fei

This study identifies convergent therapeutic targets for chemoresistance in cancer using CRISPR screens across multiple drug conditions and cancer models.

bioRxiv · Apr 24, 2024Cancer Biology

Atomic-Resolution Prediction of Degrader-mediated Ternary Complex Structures by Combining Molecular Simulations with Hydrogen Deuterium Exchange

T. Dixon, D. MacPherson, B. Mostofian, T. Dauzhenka, S. Lotz, D. McGee, S. Shechter, U. Shrestha, R. Wiewiora, Z. A. McDargh, F. Pei, R. Pal, J. V. Ribeiro, T. Wilkerson, V. Sachdeva, , J. A. Izaguirre

This paper predicts atomic-resolution structures of degrader-mediated ternary complexes using combined HDX-MS and molecular dynamics simulations, validated by experimental data.

bioRxiv · Sep 26, 2021 · PreprintBiophysics