T. Eguether

Partial loss of colonic primary cilia promotes inflammation and carcinogenesis

This study shows that reduced colonic primary cilia in fibroblasts promotes inflammation and cancer in mouse models and human disease.

Uncoupling Intraflagellar Transport and Primary Cilia Formation Demonstrates Deep Integration of IFT in Hedgehog Signaling

The paper shows IFT is involved in hedgehog signaling dynamics but not required for smoothened delivery to cilia.