ImmunologybioRxivPreprint
Induction of transposable element expression is central to innate sensing
D. C. Rookhuizen, P.-E. Bonte, M. Ye…·S. Amigorena
The paper shows that exogenous PAMPs epigenetically activate LINE1 TEs, which engage cGAS to enhance innate immune responses.
DOI 10.1101/2021.09.10.457789