A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a non-hemophiliac state
Y. Teranishi-Ikawa, T. Soeda, H. Koga, K. Yamaguchi, K. Kato, K. Esaki, K. Asanuma, M. Funaki, M. Ichiki, Y. Ikuta, S. Ito, E. Joyashiki, S.-I. Komatsu, A. Muto, K. Nishimura, , T. Igawa
This paper reports a bispecific antibody NXT007 that shows improved hemostatic activity in hemophilia A monkeys, equivalent to FVIII levels, with lower dosing requirements and longer intervals.
bioRxiv · Dec 19, 2022Bioengineering