Author

A. Muto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

H. Nishizawa· 2 shared H. Shima· 2 shared K. Igarashi· 2 shared A. Matsusaki· 1 shared B. K. K. Callens· 1 shared E. Joyashiki· 1 shared H. Koga· 1 shared H. Konishi· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

H. Nishizawa

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cysteine restriction induces ferroptosis depending on the polyamine biosynthetic pathway in hepatic cancer cells

K. Tada, H. Nishizawa, H. Shima, A. Muto, M. Wada, K. Igarashi

This study shows that cysteine restriction induces ferroptosis in hepatic cancer cells via the polyamine biosynthetic pathway, but not in normal hepatocytes.

bioRxiv · Feb 29, 2024Biochemistry

TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and -independent mechanisms without relying on heme and FBXO22

L. Liu, M. Matsumoto, M. Matsui-Watanabe, T. Nakagawa, Y. Nagasawa, J. Pang, B. K. K. Callens, A. Muto, K. Ochiai, H. Takekawa, M. Alam, H. Nishizawa, M. Shirouzu, H. Shima, K. Nakayama, K. Igarashi

bioRxiv · Feb 15, 2024Biochemistry

A bispecific antibody NXT007 exerts a hemostatic activity in hemophilia A monkeys enough to keep a non-hemophiliac state

Y. Teranishi-Ikawa, T. Soeda, H. Koga, K. Yamaguchi, K. Kato, K. Esaki, K. Asanuma, M. Funaki, M. Ichiki, Y. Ikuta, S. Ito, E. Joyashiki, S.-I. Komatsu, A. Muto, K. Nishimura, , T. Igawa

This paper reports a bispecific antibody NXT007 that shows improved hemostatic activity in hemophilia A monkeys, equivalent to FVIII levels, with lower dosing requirements and longer intervals.

bioRxiv · Dec 19, 2022Bioengineering