T. Kohn

Dependence of aerosol-borne influenza A virus infectivity on relative humidity and aerosol composition

This study investigates how relative humidity and aerosol composition affect influenza A virus infectivity in aerosol particles, finding that low humidity and efflorescence preserve infectivity longer than intermediate humidity conditions.

Impact of Organic Compounds on the Stability of Influenza A Virus in deposited 1-ul droplets

This study examines how organic compounds affect the stability of influenza A virus in droplets, finding that proteins enhance virus stability by altering drying dynamics and efflorescence RH.

Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria.

This study shows that respiratory commensal bacteria enhance the stability of influenza A virus in droplets and aerosols, suggesting the microbiota may influence viral transmission risks.

Salt supersaturation as accelerator of influenza A virus inactivation in 1-μl droplets

This study quantifies how salt concentration affects influenza A virus inactivation in drying droplets and explains airborne virus transmission mechanisms.

Influence of amino acid substitutions in capsid proteins of coxsackievirus B5 on free chlorine and thermal inactivation

This study investigates how amino acid substitutions in coxsackievirus B5 capsid proteins affect sensitivity to free chlorine and heat, finding that capsid changes have a minor role in chlorine sensitivity but reduce heat sensitivity in specific mutants.

The early communication stages between serine proteases and enterovirus capsids in the race for viral disintegration

This study identifies molecular mechanisms by which serine proteases interact with enterovirus capsids, revealing specific residues and structural sites that determine viral inactivation.

Uptake without inactivation of human adenovirus type 2 by Tetrahymena pyriformis ciliates

This study shows Tetrahymena pyriformis ciliates efficiently remove human adenovirus type 2 from water but do not inactivate it, acting as both a sink and potential reservoir for infectious viruses.

Inactivation mechanisms of Influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS.

This study identifies how Influenza A virus inactivates under acidic aerosol conditions using HDX-MS, revealing HA conformational changes and M1 unfolding as key mechanisms.

Observed Kinetics of Enterovirus Inactivation by Free Chlorine Is Host Cell-Dependent

This study shows that free chlorine inactivates enteroviruses at different rates depending on the host cell used, while UV and heat show consistent inactivation rates across host cells.

The novel shapeshifting bacterial phylum Saltatorellota

This paper discovers a new bacterial phylum, Saltatorellota, capable of shape-shifting and amoeba-like movement, challenging the notion of bacterial morphological rigidity.