Human CD4+/CD8α+ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation
S. Touch, E. Godefroy, N. Rolhion, C. Danne, C. Oeuvray, M. Straube, C. Galbert, L. Brot, I. Alonso Salgueiro, S. Chadi, T. Ledent, J. M. Chatel, P. Langella, F. Jotereau, F. Altare, H. Sokol
The paper shows that human CD4+/CD8α+ regulatory T cells induced by Faecalibacterium prausnitzii reduce intestinal inflammation in a mouse model and correlate with disease activity in IBD patients.
bioRxiv · Mar 22, 2022Immunology