Author

T. Lopez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein design· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

C. F. Arias· 2 shared R. M. DuBois· 2 shared S. Lopez· 2 shared A. Ghosh· 1 shared C. Aguilera-Flores· 1 shared C. Alpuche-Aranda· 1 shared C. Gaspar-Castillo· 1 shared C. Sandoval-Jaime· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

C. F. Arias

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Antigenic determinants of HAstV-VA1 neutralization and their relevance in the human immune response

I. Ramirez-Bello, T. Lopez, R. Espinosa, A. Ghosh, K. Green, L. Riano-Umbarila, C. Gaspar-Castillo, C. Alpuche-Aranda, S. Lopez, R. M. DuBois, C. F. Arias

This paper identifies three neutralizing monoclonal antibodies against HAstV-VA1 and maps their epitopes, revealing four antigenic sites and immune pressure-driven mutations in a patient with encephalitis.

bioRxiv · Mar 5, 2024 · PreprintMicrobiology

The capsid precursor protein of astrovirus VA1 is proteolytically processed intracellularly

C. Aguilera-Flores, T. Lopez, C. Sandoval-Jaime, E. I. Perez, S. Lopez, R. M. DuBois, C. F. Arias

This study shows that the astrovirus VA1 capsid precursor protein is proteolytically processed intracellularly to form mature infectious particles, independent of trypsin and caspases.

bioRxiv · Apr 28, 2022Microbiology

REP-X: An Evolution-guided Strategy for the Rational Design of Cysteine-less Protein Variants

K. Dalton, T. Lopez, V. Pande, J. Frydman

The paper introduces REP-X, a tool that uses evolutionary information to design cysteine-less protein variants while maintaining activity and stability.

bioRxiv · Oct 8, 2019Biochemistry