Engineering Modular and Tunable Single Molecule Sensors by Decoupling Sensing from Signal Output
L. Grabenhorst, M. Pfeiffer, T. Schinkel, M. Kümmerlin, J. B. Maglic, G. A. Brüggenthies, F. Selbach, A. T. Murr, P. Tinnefeld, V. Glembockyte
This paper introduces modular and tunable single-molecule sensors using DNA origami scaffolds to detect biomolecules with adjustable response windows and specificity.
bioRxiv · Nov 6, 2023Biophysics