Cell BiologybioRxivPreprint
Depletion of tropomyosin 1.6 promotes matrix-degrading phenotype in TGF-β1-induced myofibroblast
C. L. Wu, G.-H. Lee, B. Y. Chen…·M.-J. Tang
This study shows that Tpm1.6 depletion reduces TGF-β1-induced myofibroblast contractility and enhances collagen degradation, suggesting it as a therapeutic target for fibrosis.
DOI 10.1101/2023.12.08.570775