Curvature of the retroviral capsid assembly is modulated by a molecular switch
T. Thame, B. Alexander, X. Qiao, J. Jeon, R. Weed, K. Janicki, B. Hu, P. L. Gorkov, I. Hung, Z. Gan, J. R. Perilla, B. Chen
The paper identifies key residues that enable a molecular switch in retroviral capsid proteins, allowing curvature changes during capsid assembly.
bioRxiv · Dec 26, 2020Biophysics