Author

T. Viswanathan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

L. Martinez-Sobrido· 2 shared N. Dai· 2 shared S. Arya· 2 shared S. Qi· 2 shared S.-H. Chan· 2 shared Y. K. Gupta· 2 shared A. Misra· 1 shared F. Oladunni· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBiochemistry

L. Martinez-Sobrido

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2 papers

Recent·Most cited

A metal ion orients mRNA to ensure accurate 2'-O ribosyl methylation of the first nucleotide of the SARS-CoV-2 genome

T. Viswanathan, A. Misra, S.-H. Chan, S. Qi, N. Dai, S. Arya, L. Martinez-Sobrido, Y. K. Gupta

The paper reports structures of the SARS-CoV-2 nsp16/nsp10 enzyme complex before and after RNA product release, revealing conformational changes and the role of a metal ion in 2'-O methylation of the first nucleotide.

bioRxiv · Mar 12, 2021Biochemistry

Structural Basis of RNA Cap Modification by SARS-CoV-2 Coronavirus

T. Viswanathan, S. Arya, S.-H. Chan, S. Qi, N. Dai, R. A. Hromas, J.-G. Park, F. Oladunni, L. Martinez-Sobrido, Y. K. Gupta

The paper reports the high-resolution structure of SARS-CoV-2 nsp16/nsp10 complex during mRNA cap methylation, revealing conformational changes and a novel ligand-binding site for antiviral targeting.

bioRxiv · Apr 26, 2020Biophysics